BP206TSemester 23 creditsTheory
Physical Pharmaceutics
Complete unit-wise syllabus for BP206T as per the PCI B.Pharm NEP 2020 curriculum (Semester 2 — Organic Chemistry + Biostatistics).
URL:
https://pharmacode.vercel.app/syllabus/semester-2/bp206t-physical-pharmaceutics/Unit-wise Syllabus
5 Units1
Matter and Thermodynamics9 Hours- States of matter: gases, liquids, solids — properties and transitions; intermolecular forces in pharmaceutical systems
- Thermodynamics: laws of thermodynamics; Gibbs free energy and its significance; enthalpy and entropy in pharmaceutical processes
- Phase equilibria: phase rule, phase diagrams, eutectic mixtures — pharmaceutical applications
2
Solutions and Solubility9 Hours- Solubility: definitions, types, factors affecting solubility; solubility expressions; ideal and non-ideal solutions
- Dissolution kinetics: Noyes-Whitney equation; intrinsic dissolution rate; factors affecting dissolution; dissolution testing in drug release
- Diffusion: Fick's laws; diffusion across membranes; dialysis; ultrafiltration; pharmaceutical applications
3
Surface and Interfacial Phenomena9 Hours- Surface tension and surface energy; measurement methods; temperature dependence
- Surfactants: classification, HLB system, mechanism of action; pharmaceutical applications (wetting, solubilization, emulsification)
- Adsorption: types (physical and chemical); Freundlich and Langmuir adsorption isotherms; pharmaceutical applications
4
Colloidal Dispersions, Emulsions and Suspensions8 Hours- Colloidal systems: classification, properties (Tyndall effect, Brownian motion, zeta potential); stability and flocculation
- Emulsions: definition, types (O/W, W/O), emulsifying agents, preparation methods; stability testing; HLB and its applications
- Suspensions: definition, types, sedimentation theory (Stokes' law), flocculation and deflocculation; formulation principles
5
Rheology10 Hours- Viscosity: definition, types (Newtonian, non-Newtonian flow); measurement methods (Ostwald viscometer, Brookfield viscometer)
- Non-Newtonian systems: plastic, pseudoplastic, dilatant, thixotropic flow; thixotropy in pharmaceutical formulations
- Viscoelastic properties; applications in formulation of semi-solids, suspensions, and polymer solutions
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Other subjects in Semester 2
BP201TApplied Biostatistics and Data Analytics for Pharmaceutical SciencesBP202TBiochemistryBP203THuman Anatomy, Physiology and Pathophysiology IIBP204TPharmaceutical Organic ChemistryBP205TPharmacognosy and PhytochemistryBP207P–BP212P + SECPracticals + SEC Elective (Communication Skills / Mental Well-Being / Computer Operations)