BP504TSemester 52 creditsTheory
Pharmaceutical Dosage Form II
Complete unit-wise syllabus for BP504T as per the PCI B.Pharm NEP 2020 curriculum (Semester 5 — QA + Innovation + Drug Delivery).
URL:
https://pharmacode.vercel.app/syllabus/semester-5/bp504t-pharmaceutical-dosage-form-ii/Unit-wise Syllabus
5 Units1
Controlled Release Drug Delivery Systems6 Hours- Rationale for controlled release; advantages and limitations; classification: sustained release, extended release, pulsatile release, delayed release
- Diffusion-controlled systems: reservoir and matrix types; Higuchi equation; erosion-controlled and osmotic systems (OROS)
- Biopharmaceutical Classification System (BCS): Class I-IV; biopharmaceutics and its impact on CDDS design; IVIVC
2
Transdermal Drug Delivery Systems6 Hours- Skin as a barrier: anatomy, permeation routes; factors affecting skin penetration (physicochemical properties, skin condition)
- Transdermal patches: types (membrane-controlled, matrix, drug-in-adhesive, microreservoir); excipients; permeation enhancers; manufacturing
- Marketed transdermal products: nitroglycerin, scopolamine, nicotine, fentanyl, oestradiol patches — design and clinical use
3
Ocular, Nasal and Pulmonary Drug Delivery6 Hours- Ocular drug delivery: anatomy and barriers; conventional (eye drops, ointments) and novel (ocular inserts, nanoparticles, contact lenses) systems; factors affecting ocular bioavailability
- Nasal drug delivery: anatomy; drug absorption via nasal route; formulation considerations; nasal sprays, nasal gels; systemic delivery via nasal route
- Pulmonary drug delivery: anatomy; MDI, DPI, nebulisers — formulation, devices, particle size considerations; regulatory requirements
4
Targeted Drug Delivery — Nanoparticulate Systems6 Hours- Targeted drug delivery: concept; passive (EPR effect) and active targeting (receptor-mediated); targeted cancer therapy
- Liposomes: structure, preparation (thin film hydration, extrusion), characterization (size, zeta potential, entrapment efficiency); Doxil, AmBisome — marketed products
- Polymeric nanoparticles, solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC) — preparation, characterization, applications
5
Novel Drug Delivery Concepts6 Hours- Dendrimers: structure, types (PAMAM, poly-L-lysine), surface functionalisation, drug loading, pharmaceutical applications
- Microspheres and microcapsules: preparation by emulsification-solvent evaporation, spray drying, ionotropic gelation; applications in CDDS
- Hydrogels: classification, cross-linking mechanisms; smart hydrogels (pH-responsive, thermosensitive); applications in drug delivery and tissue engineering
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What's coming next on this page
- Reference textbooks and recommended reading list
- Previous year question papers (PYQ)
- Topic-wise short notes and revision summaries
- Suggested external resources and video tutorials
Other subjects in Semester 5
BP501TBiomedicinal ChemistryBP502TIndustrial PharmacognosyBP503TInnovation and Startup EcosystemBP505TPharmaceutical Quality AssuranceBP506TSystemic Pharmacology IIBP507PBiomedicinal Chemistry (Practical)BP508PIndustrial Pharmacognosy (Practical)BP509PPharmaceutical Dosage Form II (Practical)BP510PSystemic Pharmacology II (Practical)