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BP407PSemester 41 creditsPractical

Medicinal Chemistry (Practical)

Complete unit-wise syllabus for BP407P as per the PCI B.Pharm NEP 2020 curriculum (Semester 4 — Medicinal Chemistry + 1st Internship).

URL:https://pharmacode.vercel.app/syllabus/semester-4/bp407p-medicinal-chemistry-practical/

Course Objectives

  • Comprehend the fundamental principles of drug synthesis, assay, and monograph analysis.
  • Acquire practical skills in the synthesis of selected drug molecules and intermediates.
  • Develop proficiency in performing qualitative and quantitative assays of drugs.
  • Understand the requirements and procedures involved in drug monograph analysis.
  • Apply appropriate techniques and methodologies for the preparation, assay, and monograph analysis of various drugs.

Unit-wise Syllabus

1 Units
1
Laboratory Practicals & Experiments (45 Hours)45 Hours
  • 1. Preparation of Drugs / Intermediates a. Aspirin b. Benzotriazole c. Benzocaine d. Phenytoin e. Dibenzalacetone f. Paracetamol
  • 2. Assay of Drugs (Any 3) a. Aspirin b. Ibuprofen c. Furosemide d. Paracetamol
  • 3. Monograph Analysis (Any 3) a. Paracetamol b. Aspirin c. Phenobarbital d. Diclofenac e. Phenytoin

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Recommended Textbooks & References

  1. 1. Abraham, D. J. and Rotella, D. P. Burger’s Medicinal Chemistry, Drug Discovery and Development. John Wiley & Sons.
  2. Beckett, A. H. and Stenlake, J. B. Practical Pharmaceutical Chemistry. CBS Publishers & Distributors.
  3. Furniss, B. S., Hannaford, A. J., Smith, P. W. G. and Tatchell, A. R. Vogel’s Textbook of Practical Organic Chemistry. Pearson Education.
  4. Indian Pharmacopoeia Commission. Indian Pharmacopoeia. Indian Pharmacopoeia Commission.
  5. Kar, A. Advanced Practical Medicinal Chemistry. New Age International Publishers.
  6. Lednicer, D. The Organic Chemistry of Drug Synthesis. John Wiley & Sons.
  7. Moffat, A. C., Osselton, M. D. and Widdop, B. Clarke’s Analysis of Drugs and Poisons. Pharmaceutical Press.
  8. United States Pharmacopeial Convention. United States Pharmacopeia–National Formulary (USP–NF). United States Pharmacopeial Convention.
  9. Vogel, A. I. Vogel’s Textbook of Quantitative Chemical Analysis. Longman Scientific & Technical.

What's coming next on this page

  • Previous year question papers (PYQ)
  • Topic-wise short notes and revision summaries
  • MCQs and self-assessment quizzes
  • Suggested external resources and video tutorials