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BP106TSemester 13 creditsTheory

Pharmaceutical Inorganic and Analytical Chemistry

Complete unit-wise syllabus for BP106T as per the PCI B.Pharm NEP 2020 curriculum (Semester 1 — Python + Core Sciences Foundation).

All Sem 1 Subjects
URL:https://pharmacode.vercel.app/syllabus/semester-1/bp106t-pharmaceutical-inorganic-and-analytical-chemistry/

Unit-wise Syllabus

5 Units
1
Introduction to Pharmaceutical Analysis and Impurities7 Hours
  • Different techniques of analysis; methods of expressing strength of solutions; primary and secondary standards with examples
  • Sources of errors; types of errors; methods of minimizing errors; accuracy, precision, and significant figures
  • Definition, types, contents, and regulatory importance of impurities; limit tests for chloride, sulphate, iron, arsenic, lead, heavy metals; modified limit tests
2
Acid-Base Chemistry, Buffer Systems and Major Electrolytes8 Hours
  • Definition of acids, bases, buffers; pH scale and significance; buffer equation; calculation of pH for buffer solutions; isotonicity and application in IV fluids and ophthalmic solutions
  • Major extra- and intracellular electrolytes; functions of major physiological ions
  • Electrolytes used in replacement therapy: sodium chloride, potassium chloride, calcium chloride, ORS; physiological acid-base balance
3
Titrimetric Methods of Analysis14 Hours
  • Acid-base titrations: theories of indicators, classification; preparation and standardization of HCl and NaOH; neutralization curves; assay of ammonium hydroxide. Non-aqueous titrations: types of solvents; acidimetric and alkalimetric titrations; estimation of sodium benzoate
  • Precipitation titrations and gravimetry: Mohr's, Volhard's, Modified Volhard's, Fajans methods; estimation of barium sulphate by gravimetry
  • Complexometric titrations: metal ion indicators, masking/demasking reagents; preparation and standardization of disodium EDTA; estimation of magnesium sulphate and calcium gluconate
  • Redox titrations: oxidation-reduction concepts; types — permanganometry, cerimetry, iodimetry, iodometry, titrations with potassium iodate
4
Gastrointestinal Agents and Radiopharmaceuticals10 Hours
  • Gastrointestinal agents — Acidifiers: sodium acid phosphate, dilute HCl. Antacids: ideal properties, combinations, sodium bicarbonate, aluminium hydroxide gel
  • Agents promoting bowel movement: magnesium hydroxide, sodium orthophosphate, sodium potassium tartrate, magnesium trisilicate
  • Antimicrobials: potassium permanganate, boric acid, hydrogen peroxide, chlorinated lime, iodine and preparations
  • Radiopharmaceuticals: basics of radioactivity; applications of Sodium Iodide I-131, Technetium-99m, Cobalt-60, Phosphorus-32; safe handling, storage, and disposal as per regulatory guidelines
5
Miscellaneous Inorganic Pharmaceutical Compounds6 Hours
  • Expectorants: potassium iodide, ammonium chloride
  • Emetics: copper sulphate, sodium potassium tartrate
  • Haematinics: ferrous sulphate, ferrous gluconate
  • Poison and Antidote: definition, classification of antidotes; sodium thiosulphate

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